THE SCIENCE

The science behind our products

Qallo offers QFocus and QSleep, two food supplements with pharmaceutical grade and scientifically backed ingredients. Both products have been designed for gamers and Esports athletes who take their health and in-game performance seriously. Our products are approved by the Belgian Federal Agency for the Safety of the Food Chain, one of the most rigorous and renowned administrations on food supplementation in the world.

Our mission is to create nutritional products that empower gamers and esports athletes to reach their full potential in a scientifically backed and responsible way. All our products are vegan, sugar-free and non-addictive.

Our production facility is located in Belgium, the home of world class pharmaceuticals, and adheres to the highest quality standards.

QFocus is an adaptogenic and nootropic based supplement with proven short term and long term benefits. It supports learning, brain performance and memorization abilities, improves concentration and contributes to cognitive performance and reduction of fatigue. QFocus does not contain caffeine.

QFocus ingredients

Bacopa extract (Bacopa Monnieri)

Bacopa Monnieri, also known as brahmi, is a plant that has been used in traditional Indian medicine (Ayurveda). It is perennial creeping plant belonging to the family Scrophulariaceae, is majorly found in wet, damp, and marshy areas throughout India.

Scientific research that discusses the potential benefits of Bacopa Monnieri:

    • Pase MP, Kean J, Sarris J, Neale C, Scholey AB, Stough C. The cognitive-enhancing effects of Bacopa monnieri: a systematic review of randomized, controlled human clinical trials. J Altern Complement Med. 2012;18(7):647-652. doi:10.1089/acm.2011.0367
    • Kean JD, Downey LA, Stough C. A systematic review of the Ayurvedic medicinal herb Bacopa monnieri in child and adolescent populations. doi:10.1016/j.ctim.2016.09.002
    • Kongkeaw C, Dilokthornsakul P, Thanarangsarit P, Limpeanchob N, Norman Scholfield C. Meta-analysis of randomized controlled trials on cognitive effects of Bacopa monnieri extract. J Ethnopharmacol. 2014;151(1):528-535. doi:10.1016/j.jep.2013.11.008
    • Benson S, Downey LA, Stough C, Wetherell M, Zangara A, Scholey A. An acute, double-blind, placebo-controlled cross-over study of 320 mg and 640 mg doses of Bacopa monnieri (CDRI 08) on multitasking stress reactivity and mood. Phytother Res. 2014;28(4):551-559. doi:10.1002/ptr.5029
    • Cicero AF, Bove M, Colletti A, et al. Short-Term Impact of a Combined Nutraceutical on Cognitive Function, Perceived Stress and Depression in Young Elderly with Cognitive Impairment: A Pilot, Double-Blind, Randomized Clinical Trial. J Prev Alzheimers Dis. 2017;4(1):12-15

Ginseng extract (Panax ginseng)

A slow-growing, short plant with fleshy roots that can be classified three ways, depending on how long it is grown: fresh, white or red. There are many types of this herb, but the most popular are American ginseng (Panax quinquefolius) and Asian ginseng (Panax ginseng). Ginseng has been used in traditional Chinese medicine for centuries.

Scientific research that discusses the potential benefits of Panax Ginsseng:

    • Arring NM, Millstine D, Marks LA, Nail LM. Ginseng as a Treatment for Fatigue: A Systematic Review. doi:10.1089/acm.2017.0361
    • Lee NH, Son CG. Systematic review of randomized controlled trials evaluating the efficacy and safety of ginseng. J Acupunct Merdian Stud. 2011;4(2):85-97 doi:10.1016/S2005-2901(11)60013-7
    • Shergis JL, Zhang AL, Zhou W, Xue CC. Panax ginseng in randomised controlled trials: a systematic review. Phytother Res. 2013;27(7):949-965.doi:10.1002/ptr.4832

Oat extract (Avena Sativa)

Oat straw comes from the unripened Avena sativa plant, which is commonly grown in Northern Europe and North America. As an extract, oat straw is often sold as a tincture but can also be found in powder and capsule form.

Scientific research that discusses the potential benefits of Avena Sativa (Oat Extract):

    • Berry NM, Robinson MJ, Bryan J, Buckley JD, Murphy KJ, Howe PR. Acute effects of an Avena sativa herb extract on responses to the Stroop Color-Word. test. J Altern Complement Med. 2011;17(7):635-637. doi:10.1089/acm.2010.0450
    • Dimpfel W, Storni C, Verbruggen M. Ingested oat herb extract (Avena sativa) changes EEG spectral frequencies in healthy subjects. J Altern Complement Med. 2011;17(5):427-434. doi:10.1089/acm.2010.0143
    • Kennedy DO, Jackson PA, Forster J, et al. Acute effects of a wild green-oat (Avena sativa) extract on cognitive function in middle-aged adults: A double-blind, placebo-controlled, within-subjects trial. 2017;20(2):135-151. doi:10.1080/1028415X.2015.1101304
    • Singh R, De S, Belkheir A. Avena sativa (Oat), a potential neutraceutical and therapeutic agent: an overview. Crit Rev Food Sci Nutr. 2013;53(2):126-144. doi:10.1080/10408398.2010.526725
    • Wong RH, Howe PR, Coates AM, Buckley JD, Berry NM. Chronic consumption of a wild green oat extract (Neuravena) improves brachial flow-mediated dilatation and cerebrovascular responsiveness in older adults. J Hyupertens 2013;31(1):192-200. doi:10.1097/HJH.0b013e32835b04d4

Acerola extract (Malphighia Punicifolia)

Acerola cherry is a plant that is native to tropical regions of the Western Hemisphere. It’s also commonly called the West Indies cherry, Barbados cherry, or just simply “acerola.” It’s believed that the shrub-like plant originated in southern Mexico and the Caribbean.

Scientific research that discusses the potential benefits of Malphighia punicifolia:

    • Nowak D, Gośliński M, Wojtowicz E, Przygoński K. Antioxidant Properties and Phenolic Compounds of Vitamin C-Rich Juices. J Food Sci. 2018;83(8):2237-2246. doi:10.1111/1750-3841.14284
    • Prakash A, Baskaran R. Acerola, an untapped functional superfruit: a review on latest frontiers. J Food Sci Technol. 2018;55(9):3373-3384 doi:10.1007/s13197-018-3309-5

 

Phosphatidylserine

Phosphatidylcholine (PC) is a phospholipid attached to a choline particle. Phospholipids contain fatty acids, glycerol, and phosphorous. It's available in a number of foods, including soy.

Scientific research that discusses the potential benefits of Phosphatidylserine:

    • Glade MJ, Smith K. Phosphatidylserine and the human brain. Nutrition. 2015;31(6):781-786. doi:10.1016/j.nut.2014.10.014
    • Kim HY, Huang BX, Spector AA. Phosphatidylserine in the brain: metabolism and function. Prog Lipid Res. 2014;56:1-18. doi:10.1016/j.plipres.2014.06.002
    • McDaniel MA, Maier SF, Einstein GO. ""Brain-specific"" nutrients: a memory cure?. Nutrition. 2003;19(11-12):957-975. doi:10.1016/s0899-9007(03)00024-8
    • Moré MI, Freitas U, Rutenberg D. Positive effects of soy lecithin-derived phosphatidylserine plus phosphatidic acid on memory, cognition, daily functioning, and mood in elderly patients with Alzheimer's disease and dementia. Adv Ther. 2014;31(12):1247-1262. doi:10.1007/s12325-014-0165-1
    • Zhang YY, Yang LQ, Guo LM. Effect of phosphatidylserine on memory in patients and rats with Alzheimer's disease. Genet Mol Res. 2015;14(3):9325-9333. Published 2015 Aug 10. doi:10.4238/2015.August.10.13"

Acetyl L-Carnitine

Acetyl L-Carnitine is a naturally occurring amino acid derivative. Sources include whole-wheat bread and asparagus.

Scientific research that discusses the potential benefits of Acetyl L-Carnitine:

    • Malaguarnera M, Vacante M, Bertino G, et al. The supplementation of acetyl-L- carnitine decreases fatigue and increases quality of life in patients with hepatitis C treated with pegylated interferon-α 2b plus ribavirin. J Interferon Cytokine Res. 2011;31(9):653-659. doi:10.1089/jir.2011.0010
    • Malaguarnera M, Vacante M, Giordano M, et al. Oral acetyl-L-carnitine therapy reduces fatigue in overt hepatic encephalopathy: a randomized, double-blind, placebo-controlled study. Am J Clin Nutr. 2011;93(4):799-808. doi:10.3945/ajcn.110.007393
    • Malaguarnera M. Carnitine derivatives: clinical usefulness. Curr Opin Gastroenterol. 2012;28(2):166-176. doi:10.1097/MOG.0b013e3283505a3b
    • McDaniel MA, Maier SF, Einstein GO. ""Brain-specific"" nutrients: a memory cure?. Nutrition. 2003;19(11-12):957-975. doi:10.1016/s0899-9007(03)00024-8
    • Veronese N, Stubbs B, Solmi M, Ajnakina O, Carvalho AF, Maggi S. Acetyl-L- Carnitine Supplementation and the Treatment of Depressive Symptoms: A Systematic Review and Meta-Analysis. Psychosom Med. 2018;80(2):154-159. doi:10.1097/PSY.0000000000000537

Magnesium

Magnesium is a mineral vital for the proper functioning of your body. The human body can not produce magnesium, so we need to obtain it from our diet. Magnesium can be found in many sources, like for example sea salt.

Scientific research that discusses the potential benefits of Magnesium:

    • Boyle NB, Lawton C, Dye L. The Effects of Magnesium Supplementation on Subjective Anxiety and Stress-A Systematic Review. Nutrients. 2017;9(5):429. Published 2017 Apr 26. doi:10.3390/nu9050429
    • Nielsen FH, Johnson LK, Zeng H. Magnesium supplementation improves indicators of low magnesium status and inflammatory stress in adults older than 51 years with poor quality sleep. Magnes Res. 2010;23(4):158-168. doi:10.1684/mrh.2010.0220
    • Pouteau E, Kabir-Ahmadi M, Noah L, et al. Superiority of magnesium and vitamin B6 over magnesium alone on severe stress in healthy adults with low magnesemia: A randomized, single-blind clinical trial. PLoS One. 2018;13(12):e0208454. Published 2018 Dec 18. doi:10.1371/journal.pone.0208454

Vitamin B6

Vitamin B6, also known as pyridoxine, is a water-soluble vitamin that your body needs for several functions.

Scientific research that discusses the potential benefits of Vitamin B6:

    • Pouteau E, Kabir-Ahmadi M, Noah L, et al. Superiority of magnesium and vitamin B6 over magnesium alone on severe stress in healthy adults with low magnesemia: A randomized, single-blind clinical trial. PLoS One. 2018;13(12):e0208454. Published 2018 Dec 18. doi:10.1371/journal.pone.0208454

QSleep consists of multiple plant extracts that helps to cope with stress and helpts to maintain a natural sleep. It supports relaxation, calmness and both mental and physical well-being.

QSleep ingredients

Valerian root (Valeriana officinialis)

Valeriana officinalis, commonly known as valerian, is an herb native to Asia and Europe. It is now also grown in the US, China and other countries. Flowers from the valerian plant were used to make perfume centuries ago, and the root portion has been used in traditional medicine for at least 2,000 years. Unlike its delicately scented flowers, valerian root has a very strong, earthy odor. The name “valerian” is derived from the Latin verb valere, which means “to be strong” or “to be healthy.

Scientific research that discusses the potential benefits of Valerian root:

    • Dumur J, Csajka C, Pavec O, et al. Quelle alternative aux benzodiazépines, Z- pills et autres hypnotiques pour les personnes âgées ?: Mélatonine, valériane ou clométhiazole [Which alternative to benzodiazepines, Z-pills and other hypnotics for aged people ? Melatonin, valerian, or clomethiazole] Rev Med Suisse 2018;14(626):2018-2023
    • Faustino TT, Almeida RB, Andreatini R. Plantas medicinais no tratamento do transtorno de ansiedade generalizada: uma revisão dos estudos clínicos controlados [Medicinal plants for the treatment of generalized anxiety disorder: a review of controlled clinical studies]. Braz J Psychiatry. 2010;32(4):429-436. doi:10.1590/s1516-44462010005000026
    • Leach MJ, Page AT. Herbal medicine for insomnia: A systematic review and meta-analysis. Sleep Med Rev. 2015;24:1-12. doi:10.1016/j.smrv.2014.12.003
    • Savage K, Firth J, Stough C, Sarris J. GABA-modulating phytomedicines for anxiety: A systematic review of preclinical and clinical evidence. Phytother Res. 2018;32(1):3-18. doi:10.1002/ptr.5940
    • Taavoni S, Ekbatani N, Kashaniyan M, Haghani H. Effect of valerian on sleep quality in postmenopausal women: a randomized placebo-controlled clinical trial Menopause. 2011;18(9):951-955. doi:10.1097/gme.0b013e31820e9acf

Passion flower (Passiflora incarnata)

There are about 500 known species of passionflower. This family of plants is also known as Passiflora. Spanish explorers learned about passionflower from native Peruvians. They named these plants for their resemblance to a crucifix. In Christian traditions, “the Passion” is a term used to describe the final period of Jesus Christ’s life, including his crucifixion.

Scientific research that discusses the potential benefits of Passion flower:

    • Aslanargun P, Cuvas O, Dikmen B, Aslan E, Yuksel MU. Passiflora incarnata Linneaus as an anxiolytic before spinal anesthesia. J Anesth. 2012;26(1):39-44. doi:10.1007/s00540-011-1265-6
    • Faustino TT, Almeida RB, Andreatini R. Plantas medicinais no tratamento do transtorno de ansiedade generalizada: uma revisão dos estudos clínicos controlados [Medicinal plants for the treatment of generalized anxiety disorder: a review of controlled clinical studies]. Braz J Psychiatry. 2010;32(4):429-436. doi:10.1590/s1516-44462010005000026
    • Lakhan SE, Vieira KF. Nutritional and herbal supplements for anxiety and anxiety-related disorders: systematic review. Nutr J. 2010;9:42. Published 2010 Oct 7. doi:10.1186/1475-2891-9-42
    • Lee J, Jung HY, Lee SI, Choi JH, Kim SG. Effects of Passiflora incarnata Linnaeus on polysomnographic sleep parameters in subjects with insomnia disorder: a double-blind randomized placebo-controlled study. Int Clin Psychopharmacol. 2020;35(1):29-35. doi:10.1097/YIC.0000000000000291
    • Ngan A, Conduit R. A double-blind, placebo-controlled investigation of the effects of Passiflora incarnata (passionflower) herbal tea on subjective sleep quality. Phytother Res. 2011;25(8):1153-1159. doi:10.1002/ptr.3400
    • Sarris J, Panossian A, Schweitzer I, Stough C, Scholey A. Herbal medicine for depression, anxiety and insomnia: a review of psychopharmacology and clinical evidence. Eur Neuropsychopharmacol. 2011;21(12):841-860. doi:10.1016/j.euroneuro.2011.04.002
    • Savage K, Firth J, Stough C, Sarris J. GABA-modulating phytomedicines for anxiety: A systematic review of preclinical and clinical evidence. Phytother Res. 2018;32(1):3-18. doi:10.1002/ptr.5940

Lemon balm (Melissa officinalis)

Lemon balm is a lemon-scented herb that comes from the same family as mint. The herb is native to Europe, North Africa, and West Asia, but it’s grown around the world.

Scientific research that discusses the potential benefits of Lemon melissa:

    • Haybar H, Javid AZ, Haghighizadeh MH, Valizadeh E, Mohaghegh SM, Mohammadzadeh A. The effects of Melissa officinalis supplementation on depression, anxiety, stress, and sleep disorder in patients with chronic stable angina. Clin Nutr ESPEN. 2018;26:47-52. doi:10.1016/j.clnesp.2018.04.015
    • Savage K, Firth J, Stough C, Sarris J. GABA-modulating phytomedicines for anxiety: A systematic review of preclinical and clinical evidence. Phytother Res. 2018;32(1):3-18. doi:10.1002/ptr.5940

Lavender (Lavandule angustifolia)

Lavender is a well-known plant for its scent and its name derives from the Latin root “lavare,” which literally means “to wash.”The earliest recorded use of lavender dates back to ancient Egypt. There, lavender oil played a role in the mummification process.

Scientific research that discusses the potential benefits of Lavender:

    • Barić H, Đorđević V, Cerovečki I, Trkulja V. Complementary and Alternative Medicine Treatments for Generalized Anxiety Disorder: Systematic Review and Meta-analysis of Randomized Controlled Trials. Adv Ther. 2018;35(3):261-288. doi:10.1007/s12325-018-0680-6
    • Donelli D, Antonelli M, Bellinazzi C, Gensini GF, Firenzuoli F. Effects of lavender on anxiety: A systematic review and meta-analysis. 2019;65:153099. Phytomedicine. doi:10.1016/j.phymed.2019.153099
    • Perry R, Terry R, Watson LK, Ernst E. Is lavender an anxiolytic drug? A systematic review of randomised clinical trials. Phytomedicine. 2012;19(8-9):825-835. doi:10.1016/j.phymed.2012.02.013

L-tryptophane

Tryptophan is an essential amino acid that serves several important purposes, like nitrogen balance in adults and growth in infants. There are two types of tryptophan: L-tryptophan and D-tryptophan. The only difference between the two types is the orientation of the molecule. You can get tryptophan through certain foods like peanuts, pumpkine and sesame seeds, chocolate and soy.

Scientific research that discusses the potential benefits of L-tryptophane:

    • van Dalfsen JH, Markus CR. The serotonin transporter gene-linked polymorphic region (5-HTTLPR) and the sleep-promoting effects of tryptophan: A randomized placebo-controlled crossover study. J Psychopharmacol. 2019;33(8):948-954. doi:10.1177/0269881119855978
    • Sarris J, Byrne GJ. A systematic review of insomnia and complementary medicine. Sleep Med Rev. 2011;15(2):99-106. doi:10.1016/j.smrv.2010.04.001
    • Wang D, Li W, Xiao Y, et al. Tryptophan for the sleeping disorder and mental symptom of new-type drug dependence: A randomized, double-blind, placebo-controlled trial. Medicine (Baltimore). 2016;95(28):e4135. doi:10.1097/MD.0000000000004135

Melatonin

Melatonin is a hormone that tells your body when it’s time to initiate sleep. It’s produced by the pineal gland in the brain, but it’s also found in other areas, such as the eyes, bone marrow, and gut. Melatonin can be synthetically produced in a lab environment. QSleep only contains a microdose of 0,29mg to assist the natural melatonin production.

Scientific research that discusses the potential benefits of Melatonin:

    • Auld F, Maschauer EL, Morrison I, Skene DJ, Riha RL. Evidence for the efficacy of melatonin in the treatment of primary adult sleep disorders. Sleep Med Rev. 2017;34:10-22. doi:10.1016/j.smrv.2016.06.005
    • Dumur J, Csajka C, Pavec O, et al. Quelle alternative aux benzodiazépines, Z- pills et autres hypnotiques pour les personnes âgées ?: Mélatonine, valériane ou clométhiazole [Which alternative to benzodiazepines, Z-pills and other hypnotics for aged people ? Melatonin, valerian, or clomethiazole] Rev Med Suisse 2018;14(626):2018-2023
    • Ferracioli-Oda E, Qawasmi A, Bloch MH. Meta-analysis: melatonin for the treatment of primary sleep disorders. PLoS One. 2013;8(5):e63773. Published 2013 May 17. doi:10.1371/journal.pone.0063773
    • Li T, Jiang S, Han M, et al. Exogenous melatonin as a treatment for secondary sleep disorders: A systematic review and meta-analysis. Front Neuroendocrinol. 2019;52:22-28. doi:10.1016/j.yfrne.2018.06.004
    • Vural EM, van Munster BC, de Rooij SE. Optimal dosages for melatonin supplementation therapy in older adults: a systematic review of current literature. Drugs Aging. 2014;31(6):441-451. doi:10.1007/s40266-014-0178-0"

If you have any more questions about the products or the ingredients, please contact us on hello@qallo.com. We're happy to help and provide you with more information.

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